In an effort to move away from petroleum-based fuels and chemicals, White Dog Labs has developed a novel platform for the production of low cost cellulosic enzymes, which has the potential to significantly reduce the cost of 2nd generation (i.e., cellulose based) sugars - the input to 2nd generation biofuels and biochemicals.

The process is called CelZyme™, and the technology is based upon nature’s number one cellulose degrader – Clostridium thermocellum.  CelZyme was born out of the laboratory of Professor Ed Bayer at the Weizmann Institute, where he and colleagues discovered the cellulosome. Subsequently, a WDL Israeli spin-off has harnessed the thermostable, cellulosome through deep knowledge of Clostridium genetics, metabolism and process design to develop a process that uniquely delivers:

·         Optimal activity at high temperatures (70C˚) – which reduces chance for contamination.

·         Simultaneous hydrolysis of cellulose and hemicellulose through a single enzyme complex.

·         Low power requirements due to anaerobic fermentation.

·         Bolt-on design that allows CelZyme production to be co-located near conversion plants, e.g., 2nd generation ethanol.


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